BDBM18355 (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol::CHEMBL1029::MIGLUSTAT::N-Butyl-DNJ::US20230339856, Compound NB-DNJ::US9181184, 5
SMILES CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
InChI Key InChIKey=UQRORFVVSGFNRO-UTINFBMNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 18355
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition mouse glucosylceramide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GCS by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of GSG in mouse MEB5 cellsMore data for this Ligand-Target Pair